Transferrin Receptor Protein (AA 89-760) (His tag)

Catalog No. ABIN7597355

This Recombinant Transferrin Receptor protein is expressed in HEK-293 Cells.

Quick Overview for Transferrin Receptor Protein (AA 89-760) (His tag) (ABIN7597355)

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Protein Type: Recombinant

Origin: Cynomolgus

Source: HEK-293 Cells

Purity: The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.

Product Details

Protein Characteristics: AA 89-760

Purification tag / Conjugate: This Transferrin Receptor protein is labelled with His tag.

Purpose: Recombinant Cynomolgus TFRC protein with N-terminal 10xHis tag

Sequence: 10xHis tag TFRC(Cys89-Phe760)

Application Details

Application Notes: Extracellular Domain Proteins (ECD) can be used as:

• Immunogens for antibody drug development
• Reagents used for CAR-T positive cell monitoring
• Reagents for antibody screening and functional testing
• Reagents for antibody affinity measurement

Comment:

The protein was made using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Alternative Name: TFRC

Background: T9, TR, TFR, p90, CD71, TFR1, TRFR, IMD46
This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015]

Molecular Weight: predicted molecular mass of 76.6 kDa after removal of the signal peptide. The apparent molecular mass of His-cTFRC is 70-100 kDa due to glycosylation.

NCBI Accession: XP_045243212

Pathways: Transition Metal Ion Homeostasis