Neuregulin 1 Protein (NRG1) (AA 177-241)
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- Target See all Neuregulin 1 (NRG1) Proteins
- Neuregulin 1 (NRG1)
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 177-241
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- Western Blotting (WB), SDS-PAGE (SDS), Immunogen (Imm), ELISA, Activity Assay (AcA)
- Purpose
- Recombinant Human NRG1/Neuregulin-1 Protein, No tag (Active)
- Purity
- >90 % as determined by SDS-PAGE.
- Endotoxin Level
- <1 EU/μg of the protein by the LAL method.
- Biological Activity Comment
- Measured in a serum-free cell proliferation assay using human breast cancer cells (MCF-7). The ED50 for this effect is 20-100 ng/mL.
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Neuregulin 1 (NRG1) (AA 20-242) protein (Fc Tag)
NRG1 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
Neuregulin 1 (NRG1) (AA 119-237) protein (His-IF2DI Tag)NRG1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Neuregulin 1 (NRG1) (AA 1-241) protein (GST tag)NRG1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from a solution in PBS pH 7.4, 5 % Trehalose, 5 % Mannitol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
- Expiry Date
- 12 months
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- Target
- Neuregulin 1 (NRG1)
- Alternative Name
- Glial growth factor (NRG1 Products)
- Background
- Glial growth factor, Neu differentiation factor, SMDF, Breast cancer cell differentiation factor p45, Pro-neuregulin-1, membrane-bound isoform, Acetylcholine receptor-inducing activity, ARIA, GGF, HRGA, Pro-NRG1, HGL, HRG, NDF, NRG1, Sensory and motor neuron-derived factor, Heregulin
- UniProt
- Q02297
- Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
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