MICA Protein (AA 1-308) (His tag)

Catalog No. ABIN7607583

Recombinant MICA protein expressed in Mammalian Cells.

Quick Overview for MICA Protein (AA 1-308) (His tag) (ABIN7607583)

Target: MICA (MHC Class I Polypeptide-Related Sequence A (MICA))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Mammalian Cells

Application: Western Blotting (WB), ELISA, SDS-PAGE (SDS), Activity Assay (AcA), Immunogen (Imm)

Purity: >90 % as determined by SDS-PAGE.

Product Details

Protein Characteristics: AA 1-308

Purification tag / Conjugate: This MICA protein is labelled with His tag.

Purpose: Recombinant Human MICA Protein, C-His (Active)

Endotoxin Level: <0.1 EU/μg of the protein by the LAL method.

Biological Activity Comment: Immobilized recombinant human MICA (Cat #: AHH45201) at 2 μg/mL (100 μL/well) can bind NKG2D with a linear range of 0.61-14.3 ng/mL.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from a solution in PBS pH 7.4, 5 % Trehalose, 5 % Mannitol.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.

Expiry Date: 12 months

Target Details

Target: MICA (MHC Class I Polypeptide-Related Sequence A (MICA))

Alternative Name: MICA

Background: MICA, MIC-A, MHC class I polypeptide-related sequence A, PERB11.1

UniProt: Q29983

Pathways: Activation of Innate immune Response, Transition Metal Ion Homeostasis, Human Leukocyte Antigen (HLA) in Adaptive Immune Response