DcR2 Protein (AA 56-211) (His-Fc tag)

Catalog No. ABIN7678798

Recombinant DcR2 protein expressed in Mammalian Cells.

Quick Overview for DcR2 Protein (AA 56-211) (His-Fc tag) (ABIN7678798)

Target: DcR2 (TNFRSF10D) (Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Mammalian Cells

Application: Western Blotting (WB), ELISA, SDS-PAGE (SDS), Immunogen (Imm), Activity Assay (AcA)

Purity: >90 % as determined by SDS-PAGE.

Product Details

Protein Characteristics: AA 56-211

Purification tag / Conjugate: This DcR2 protein is labelled with His-Fc tag.

Purpose: Recombinant Human CD264/TNFRSF10D/TRAIL-R4 Protein, C-hFc-His (Active)

Endotoxin Level: <0.1 EU/μg of the protein by the LAL method.

Biological Activity Comment: Measured by its ability to inhibit TRAIL mediated cytotoxicity using mouse fibroblast cells (L-929) treated with TRAIL. The ED50 for this effect is 1.8-7.2 ng/mL in the presence of 20 ng/mL.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from a solution in PBS pH 7.4, 5 % Trehalose, 5 % Mannitol.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.

Expiry Date: 12 months

Target Details

Target: DcR2 (TNFRSF10D) (Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D))

Alternative Name: TRAIL-R4

Background: TRAIL-R4, TRAIL receptor 4, DcR2, TRAIL receptor with a truncated death domain, TRUNDD, DCR2, Decoy receptor 2, TNF-related apoptosis-inducing ligand receptor 4, TRAILR4, TNFRSF10D, Tumor necrosis factor receptor superfamily member 10D, CD264

UniProt: Q9UBN6

Pathways: Apoptosis