A1BG Protein (His tag)
Quick Overview for A1BG Protein (His tag) (ABIN7668143)
Target
See all A1BG ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This A1BG protein is labelled with His tag.
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Purpose
- Recombinant Human A1BG/alpha 1B-Glycoprotein Protein (His Tag)
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Sequence
- Met 1-Ser495
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Purification
- > 95 % as determined by reducing SDS-PAGE.
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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alpha-1-B Glycoprotein (A1BG) (AA 22-495) (Active) protein (His tag)
A1BG Origin: Human Host: Mammalian Cells Recombinant >90 % as determined by SDS-PAGE. WB, SDS, Imm, ELISA, AcA Active
alpha-1-B Glycoprotein (A1BG) (AA 1-373) protein (GST tag)A1BG Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
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Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Expiry Date
- 12 months
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- A1BG (alpha-1-B Glycoprotein (A1BG))
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Alternative Name
- A1BG
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Background
- A1B,ABG,GAB,HYST2477,Alpha-1B-glycoprotein (A1BG) is an approximately 80 kDa molecule that circulates in the serum. Mature human A1BG consists of five tandem Ig like domains and shares 44 % amino acid sequence identity with mouse and rat A1BG. Alternative splicing generates an isoform that lacks the signal peptide and the first Ig like domain. A1BG binds with high affinity to the cysteine rich protein CRISP-3. In pancreatic carcinoma, it is elevated in pancreatic juice as well as in the serum relative to normal patients. A1BG is abnormally excreted into the urine during idiopathic nephrotic syndrome (INS). Multiple breakdown fragments of A1BG are also present in INS urine, including one of 14 kDa that is found in steroid resistant but not steroid sensitive cases. A1BG is also elevated in the urine of patients with interstitial cystitis/painful bladder syndrome (IC/PBS).
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Molecular Weight
- 53.4 kDa
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Gene ID
- 1
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UniProt
- P04217
Target
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