Caveolin 2 Protein (CAV2) (AA 1-86) (His-GST)

Catalog No. ABIN7668325

This Recombinant Caveolin 2 protein is produced in Escherichia coli (E. coli).

Quick Overview for Caveolin 2 Protein (CAV2) (AA 1-86) (His-GST) (ABIN7668325)

Target: Caveolin 2 (CAV2)

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: Immunogen (Imm)

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 1-86

Purification tag / Conjugate: This Caveolin 2 protein is labelled with His-GST.

Purpose: Recombinant Human CAVEOLIN2/CAV2 Protein (GST,His Tag)

Sequence: Met1-Lys86

Purification: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: < 10 EU/mg of the protein as determined by the LAL method

Biological Activity Comment: Not validated for activity

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with 5 % Trehalose and 5 % Mannitol.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: Caveolin 2 (CAV2)

Alternative Name: CAVEOLIN2,CAV2

Background: CAV2,Caveolin-2,The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. This gene and related family member (CAV1) are located next to each other on chromosome 7, and express colocalizing proteins that form a stable hetero-oligomeric complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Additional isoforms resulting from the use of alternate in-frame translation initiation codons have also been described, and shown to have preferential localization in the cell (PMID:11238462). [provided by RefSeq, May 2011]

Molecular Weight:

Calculated MW: 34.4 kDa

Observed MW: 40 kDa

Gene ID: 858

UniProt: P51636

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development