CMV Glycoprotein B (CMV gB) (Inactive) Protein

Catalog No. ABIN7668548

This Recombinant CMV Glycoprotein B protein is expressed in HEK-293 Cells.

Quick Overview for CMV Glycoprotein B (CMV gB) (Inactive) Protein (ABIN7668548)

Target: CMV Glycoprotein B (CMV gB)

Protein Type: Recombinant

Biological Activity: Inactive

Origin: Human Herpesvirus 5 (HHV-5)

Source: HEK-293 Cells

Purity: > 90 %

Product Details

Purpose: Recombinant Human cytomegalovirus (HCMV) Glycoprotein B / gB Protein

Sequence: Arg 777-Val 907

Purification: > 90 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: < 1.0 EU per μg of the protein as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile Tris 50 mM, NaCl 100 mM, pH 8.0
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: CMV Glycoprotein B (CMV gB)

Alternative Name: cytomegalovirus (HCMV) Glycoprotein B

Target Type: Viral Protein

Background: Cytomegalovirus (CMV) (human herpesvirus 5) glycoprotein B, also referred as CMV gB or gB, which belongs to the herpesviridae glycoprotein B family. It is a 97-amino acid glycoprotein encoded by the ORF of UL55. Cytomegalovirus Glycoprotein B protein is the most abundant component of the envelope, a target of neutralizing antibodies with at least two defined neutralizing epitopes and an essential replication component. Cytomegalovirus Glycoprotein B protein plays important roles in HCMV entry, cell-cell spread of internal virions, and fusion of infected cells. In addition, Cytomegalovirus Glycoprotein B protein is one envelope protein capable of heparin binding. It forms a physical association with host cell annexin II independent of the presence of calcium.,Glycoprotein B,gB

Molecular Weight:

calculated_mw: 92.0 kDa

observed_mw: 130-140 kDa

UniProt: P13201