IL17D Protein (His tag)

Catalog No. ABIN7669044

Recombinant IL17D protein expressed in Escherichia coli (E. coli).

Quick Overview for IL17D Protein (His tag) (ABIN7669044)

Target: IL17D (Interleukin 17D (IL17D))

Protein Type: Recombinant

Origin: Mouse

Source: Escherichia coli (E. coli)

Purity: > 98 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This IL17D protein is labelled with His tag.

Purpose: Recombinant Mouse IL-17D protein(N-His)

Sequence: Ala 25-Arg 205

Purification: > 98 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: < 0.1 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile 20 mM sodium citrate, 0.2 M NaCl, pH 4.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: IL17D (Interleukin 17D (IL17D))

Alternative Name: IL-17D

Background: UNQ,IL 27,IL-27,IL 17D,IL 22,IL-17D,IL27,Interleukin 17D,Interleukin 27,Interleukin-17D,Interleukin-27,IL17D,UNQ3096,PRO21175,The Interleukin-17 family proteins, comprising six members (IL-17, IL-17B through IL-17F),are secreted, structurally related proteins that share a conserved cysteine-knot fold near the C-terminus, but have considerable sequence divergence at the N-terminus. IL-17 family proteins are proinflammatory cytokines that induce local cytokine production and are involved in the regulation of immune functions. Among IL-17 family members, IL-17D is most closely related to IL-17B, sharing 27 % aa sequence homology. IL-17D is expressed preferentially in skeletal muscle, heart, adipose tissue, lung, pancreas, and nervous system. Like other IL-17 family members, IL-17D modulates immune responses indirectly by stimulating the production of myeloid growth factors and chemokines including IL-6, IL-8, and GM-CSF. IL-17D has also been shown to suppress the proliferation of myeloid progenitors in colony formation assays.

Molecular Weight:

Calculated MW: 20.7 kDa

Observed MW: 25 kDa

UniProt: A0A0B4J1G4

Pathways: Cellular Response to Molecule of Bacterial Origin