PRRG2 Protein (AA 133-202) (His-GST)

Catalog No. ABIN7669484

This Recombinant PRRG2 protein is expressed in Escherichia coli (E. coli).

Quick Overview for PRRG2 Protein (AA 133-202) (His-GST) (ABIN7669484)

Target: PRRG2 (Proline-Rich Gla (G-Carboxyglutamic Acid) Polypeptide 2 (PRRG2))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: Immunogen (Imm)

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 133-202

Purification tag / Conjugate: This PRRG2 protein is labelled with His-GST.

Purpose: Recombinant Human PRRG2 Protein (GST,His Tag)

Sequence: Arg133-His202

Purification: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: < 10 EU/mg of the protein as determined by the LAL method

Biological Activity Comment: Not validated for activity

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with 5 % Trehalose and 5 % Mannitol.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: PRRG2 (Proline-Rich Gla (G-Carboxyglutamic Acid) Polypeptide 2 (PRRG2))

Alternative Name: PRRG2

Background: PRGP2,PRRG2,Proline-rich gamma-carboxyglutamic acid protein 2,TMG2,Transmembrane gamma-carboxyglutamic acid protein 2,The protein encoded by this gene is a single-pass transmembrane protein containing an N-terminal gamma-carboxyglutamic acid (Gla) domain and tandem Pro/Leu-Pro-Xaa-Tyr (PY) motifs at its C-terminal end. The Gla domain is exposed on the cell surface while the PY motifs are cytoplasmic. The PY motifs of the encoded protein have been shown to interact with YAP1, a WW domain-containing protein. Therefore, it is thought that the encoded protein may be part of a signal transduction pathway. Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight:

Calculated MW: 32.6 kDa

Observed MW: 35 kDa

Gene ID: 5639

UniProt: O14669