AMH Protein
Quick Overview for AMH Protein (ABIN7849648)
Target
See all AMH ProteinsProtein Type
Origin
Source
Application
Purity
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Purpose
- Recombinant Human Muellerian-inhibiting substance/Anti-Muellerian hormone, MIS/AMH Protein
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Anti-Mullerian Hormone (AMH) (AA 450-552) protein (His tag)
AMH Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Anti-Mullerian Hormone (AMH) protein (Myc-DYKDDDDK Tag)AMH Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 0.01 M PBS ( pH 7.4).
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Ship at 4°C. Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
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- AMH (Anti-Mullerian Hormone (AMH))
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Alternative Name
- MISAMH
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Background
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Synonyms: Muellerian-inhibiting factor, MIF, Anti-Muellerian hormone, AMH, Muellerian-inhibiting substance, MIS
Description: Recombinant human AMH protein from the region of N-terminal.
Background: Anti-Müllerian hormone (AMH), also known as Müllerian-inhibiting hormone (MIH), is a glycoprotein hormone structurally related to inhibin and activin from the transforming growth factor beta superfamily, whose key roles are in growth differentiation and folliculogenesis. AMH is a standard marker of ovarian reserve. Correlation between AMH and egg euploidy is controversial. Gat I et al study shows a correlation between AMH and aneuploidy rate, specifically among infertile patients younger than 37 years old. AMH is also a reliable marker of ovarian reserve in endometriosis patients, and it can predict follicular density in women undergoing ovarian tissue cryopreservation. In mammals, AMH prevents the development of the Müllerian ducts into the uterus and other Müllerian structures. The effect is ipsilateral, that is each testis suppresses Müllerian development only on its own side. In humans, this action takes place during the first 8 weeks of gestation. If no hormone is produced from the gonads, the Müllerian ducts automatically develop, while the Wolffian ducts, which are responsible for male reproductive parts, automatically die.
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Pathways
- Negative Regulation of Hormone Secretion
Target
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