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AMH Protein (Myc-DYKDDDDK Tag)

AMH Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2714759
  • Target See all AMH Proteins
    AMH (Anti-Mullerian Hormone (AMH))
    Protein Type
    Recombinant
    Origin
    • 9
    • 4
    • 2
    • 2
    • 2
    • 2
    Human
    Source
    • 17
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This AMH protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Anti-Muellerian Hormone / AMH protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product AMH Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Signorile, Petraglia, Baldi: "Anti-mullerian hormone is expressed by endometriosis tissues and induces cell cycle arrest and apoptosis in endometriosis cells." in: Journal of experimental & clinical cancer research : CR, Vol. 33, pp. 46, (2014) (PubMed).

  • Target
    AMH (Anti-Mullerian Hormone (AMH))
    Alternative Name
    Anti-Muellerian Hormone,amh (AMH Products)
    Synonyms
    AMH Protein, amh Protein, MIF Protein, MIS Protein, anti-Mullerian hormone Protein, amh Protein, AMH Protein, Amh Protein
    Background
    This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N- and C-terminal cleavage products that homodimerize and associate to form a biologically active noncovalent complex. This complex binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in the male embryo that would otherwise differentiate into the uterus and fallopian tubes. This protein also plays a role in Leydig cell differentiation and function and follicular development in adult females. Mutations in this gene result in persistent Mullerian duct syndrome.
    Molecular Weight
    56.6 kDa
    NCBI Accession
    NP_000470
    Pathways
    Negative Regulation of Hormone Secretion
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