CA199 Protein

Catalog No. ABIN7849660

This Native CA199 protein is produced in Human.

Quick Overview for CA199 Protein (ABIN7849660)

Target: CA199 (Carbonhydrate Antigen 199 (CA199))

Protein Type: Native

Origin: Human

Source: Human

Application: SDS-PAGE (SDS)

Purity: >90 % by SDS-PAGE

Product Details

Purpose: Native Human CA199 Protein

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 10 mM PBS, pH 7.4±0.2.

Storage: 4 °C,-20 °C

Storage Comment: Ship at 4°C.Upon receipt, aliquot andstore at -20°C for long term. Avoid repeated freeze and thaw cycles.

Target Details

Target: CA199 (Carbonhydrate Antigen 199 (CA199))

Alternative Name: CA199

Background:

Synonyms: Cancer Antigen CA19-9, CA 19-9, carbohydrate antigen 19-9, cancer antigen 19-9, sialylated Lewis antigen, Lewis antigen, Sialyl-Lewis A, Lewis a, sialylated Lewis a antigen, CA199, CA19-9, CA 199, CA 19-9

Description: Purified human Cancer Antigen CA199 protein.

Background: CA19-9 (carbohydrate antigen 19-9, also called cancer antigen 19-9 or sialylated Lewis (a) antigen) is a tumor marker that is used primarily in the management of pancreatic cancer. Guidelines from the American Society of Clinical Oncology discourage the use of CA19-9 as a screening test for cancer, particularly pancreatic cancer. The reason is that the test may be falsely normal (false negative) in many cases, or abnormally elevated in people who have no cancer at all (false positive). The main use of CA19-9 is therefore to see whether a pancreatic tumor is secreting it, if that is the case, then the levels should fall when the tumor is treated, and they may rise again if the disease recurs. CA19-9 can be elevated in many types of gastrointestinal cancer, such as colorectal cancer, esophageal cancer and hepatocellular carcinoma. Apart from cancer, elevated levels may also occur in pancreatitis, cirrhosis, and diseases of the bile ducts. It can be elevated in people with obstruction of the bile ducts.