ICA1 Protein
Quick Overview for ICA1 Protein (ABIN7849664)
Target
See all ICA1 ProteinsProtein Type
Origin
Source
Application
Purity
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Purpose
- Recombinant Human Islet cells Antigen,ICA69/ ICA1 Protein
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 10 mM Tris-HCl, 2mm EDTA with 0.1 % SKL as the preservative.
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Preservative
- Other preservative
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Storage
- 4 °C,-20 °C
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Storage Comment
- Ship at 4°C. Upon receipt, aliquot and store at -20°C or for long term. Avoid repeated freeze and thaw cycles.
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- ICA1 (Islet Cell Autoantigen 1, 69kDa (ICA1))
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Alternative Name
- ICA69 ICA1
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Background
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Synonyms: 69 kDa islet cell autoantigen, Diabetes mellitus type I autoantigen, ICA 1, ICA1, ICA69, ICAp69, Islet cell autoantigen 1 (69kD), Islet cell autoantigen 1 69 kDa, Islet cell autoantigen 1, Islet cell autoantigen 1 isoform, Islet cell autoantigen p69.
Description: Recombinant human Islet cells Antigen 69 protein with molecular weight of 72 kDa.
Background: Islet cell autoantigen 1 is a protein that in humans is encoded by the ICA1 gene.This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized.
Target
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