CKB Protein

Catalog No. ABIN7849675

This Recombinant CKB protein is produced in Escherichia coli (E. coli).

Quick Overview for CKB Protein (ABIN7849675)

Target: CKB (Creatine Kinase, Brain (CKB))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: ELISA

Purity: >80 % by SDS-PAGE

Product Details

Purpose: Recombinant Human Brain-type creatine kinase,CK-BB protein

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 20 mM Tris-HCl pH 8.0.

Storage: 4 °C,-20 °C

Storage Comment: Ship at 4°C. Upon receipt, aliquot and store at -20°C for long term. Avoid repeated freeze and thaw cycles.

Target Details

Target: CKB (Creatine Kinase, Brain (CKB))

Alternative Name: Brain-type creatine kinase,CK-BB

Background:

Synonyms: B-CK, BB-CK, BCK, brain creatine kinase, CKBB, CKb, creatine kinase B, creatine kinase brain, creatine kinase BB, Creatine Kinase brain type, Epididymis luminal protein 211, HEL 211.

Description: Recombinant Brain-type creatine kinase,CK-BB Protein.

Background: Brain-type creatine kinase also known as CK-BB is a creatine kinase that in humans is encoded by the CKB gene.The protein encoded by this gene, CK-BB, consists of a homodimer of two identical brain-type CK-B subunits. BB-CK is a cytoplasmic enzyme involved in cellular energy homeostasis, with certain fractions of the enzyme being bound to cell membranes, ATPases, and a variety of ATP-requiring enzymes in the cell. The encoded CK-BB and CK-MB proteins are members of the ATP:guanido phosphotransferase protein family. Ectopic expression (CKBE) of the B (brain) type of creatine kinase (CK-BB) in red cells and platelets is a rare, benign anomaly detected during a newborn screening program for Duchenne muscular dystrophy.