SAA Protein

Catalog No. ABIN7849678

This Recombinant SAA protein is produced in Escherichia coli (E. coli).

Quick Overview for SAA Protein (ABIN7849678)

Target: SAA (Serum Amyloid A (SAA))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: Western Blotting (WB), ELISA

Purity: >85 % by SDS-PAGE

Product Details

Purpose: Recombinant Human SAAprotein

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 50 mM Tris, 300 mM NaCl, 1 mM DTT, 1 mM EDTA & 0.2 % PMSF, pH 8.0.

Preservative: Dithiothreitol (DTT), Other preservative, PMSF

Precaution of Use: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Ship at 4°C. Upon receipt, aliquot and store at -20°C or -40°C for long term. Avoid repeated freeze and thaw cycles.

Target Details

Target: SAA (Serum Amyloid A (SAA))

Alternative Name: SAA

Background:

Synonyms: amyloid A, serum, Amyloid fibril protein AA, Amyloid protein A, PIG4, SAA, SAA2, Serum amyloid A protein, serum amyloid A-1 protein, serum amyloid A1, TP53I4, Tumor protein p53 inducible protein 4.

Description: Recombinant human serum amyloid A protein with molecular weight of 30 kDa.

Background: Serum amyloid A (SAA) proteins are a family of apolipoproteins associated with high-density lipoprotein (HDL) in plasma. Different isoforms of SAA are expressed constitutively (constitutive SAAs) at different levels or in response to inflammatory stimuli (acute phase SAAs).The conservation of these proteins throughout invertebrates and vertebrates suggests that SAAs play a highly essential role in all animals. Serum amyloid A (SAA) is also an acute phase marker that responds rapidly. It has been suggested that SAA levels correlate better with disease activity in early inflammatory joint disease than do ESR and CRP. Although largely produced by hepatocytes, more recent studies show that SAA is produced by adipocytes as well, and its serum concentration is associated with body mass index.