G-CSF Protein

Catalog No. ABIN7849686

Recombinant G-CSF protein expressed in Escherichia coli (E. coli).

Quick Overview for G-CSF Protein (ABIN7849686)

Target: G-CSF (CSF3) (Colony Stimulating Factor 3 (Granulocyte) (CSF3))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: >95 % by SDS-PAGE

Product Details

Purpose: Recombinant Human G-CSF Protein

Sterility: 0.2 μm filtered

Endotoxin Level: <0.01 EU/μg by LAL test

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Dissolve the lyophilized protein in distilled water(It is not recommended to reconstitute to a concentration<100 μg/mL.)

Buffer: Lyophilized from a 0.2 μm filtered solution of 10 mM HAc-NaAc, 150 mM NaCl, 0.004 % Tween 80, 5 % Mannitol, pH 4.0.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Ship at 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.

Target Details

Target: G-CSF (CSF3) (Colony Stimulating Factor 3 (Granulocyte) (CSF3))

Alternative Name: G-CSF

Background:

Synonyms: CSF3, C17orf33, CSF3OS, GCSF, colony stimulating factor 3

Description: Recombinant human G-CSF is produced by the E.coli system, with the target gene encoding Thr31-Pro204 expressed.

Background: Granulocyte colony-stimulating factor (G-CSF or GCSF), also known as colony-stimulating factor 3 (CSF 3), is a glycoprotein that stimulates the bone marrow to produce granulocytes and stem cells and release them into the bloodstream.Functionally, it is a cytokine and hormone, a type of colony-stimulating factor, and is produced by a number of different tissues. The pharmaceutical analogs of naturally occurring G-CSF are called filgrastim and lenograstim.G-CSF also stimulates the survival, proliferation, differentiation, and function of neutrophil precursors and mature neutrophils.

UniProt: P09919-2

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization