IL1A Protein
Quick Overview for IL1A Protein (ABIN7849706)
Target
See all IL1A ProteinsProtein Type
Origin
Source
Application
Purity
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Purpose
- Recombinant Human IL-1a Protein
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- <0.01 EU/μg by LAL test
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Interleukin 1 alpha (IL1A) (Active) protein
IL1A Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Interleukin 1 alpha (IL1A) (Active) proteinIL1A Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Interleukin 1 alpha (IL1A) (AA 113-271) protein (Fc Tag)IL1A Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining. ScA, IA, ADA, AM
Interleukin 1 alpha (IL1A) (AA 113-271) (Active) protein (His tag)IL1A Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Interleukin 1 alpha (IL1A) (AA 113-271) (Active) proteinIL1A Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Interleukin 1 alpha (IL1A) (AA 172-271) protein (GST tag)IL1A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Interleukin 1 alpha (IL1A) (AA 1-271) protein (GST tag)IL1A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Interleukin 1 alpha (IL1A) proteinIL1A Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
Interleukin 1 alpha (IL1A) proteinIL1A Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
Interleukin 1 alpha (IL1A) (AA 115-270) protein (His tag)IL1A Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 85 % SDS
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Dissolve the lyophilized protein in distilled water(It is not recommended to reconstitute to a concentration<100 μg/mL.)
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Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, pH 7.5.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Ship at 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
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- IL1A (Interleukin 1 alpha (IL1A))
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Alternative Name
- IL-1a
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Background
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Synonyms: IL1A, IL-1A, IL1, IL1-ALPHA, IL1F1, interleukin 1 alpha, IL-1 alpha, IL-1α
Description: Recombinant human IL-1a is produced by the E.coli system, with the target gene encoding Ser113-Ala271 expressed.
Background: Interleukin-1 alpha (IL-1 alpha) also known as hematopoietin 1 is a cytokine of the interleukin 1 family that in humans is encoded by the IL1A gene.In general, Interleukin 1 is responsible for the production of inflammation, as well as the promotion of fever and sepsis. IL-1α inhibitors are being developed to interrupt those processes and treat diseases.IL-1α is produced mainly by activated macrophages, as well as neutrophils, epithelial cells, and endothelial cells. It possesses metabolic, physiological, haematopoietic activities, and plays one of the central roles in the regulation of the immune responses. It binds to the interleukin-1 receptor. It is on the pathway that activates tumor necrosis factor-alpha.
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UniProt
- P01583
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Pathways
- NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints
Target
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