MMP2 Protein
Quick Overview for MMP2 Protein (ABIN7849707)
Target
See all MMP2 ProteinsProtein Type
Origin
Source
Application
Purity
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Purpose
- Recombinant Human MMP-2 Protein
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- <1 EU/μg by LAL test
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Matrix Metalloproteinase 2 (MMP2) (Active) protein
MMP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Matrix Metalloproteinase 2 (MMP2) (AA 30-660) protein (His tag)MMP2 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Matrix Metalloproteinase 2 (MMP2) (AA 1-660) protein (GST tag)MMP2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Matrix Metalloproteinase 2 (MMP2) (AA 424-660) protein (His-IF2DI Tag)MMP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Matrix Metalloproteinase 2 (MMP2) (AA 109-660) protein (His-IF2DI Tag)MMP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Dissolve the lyophilized protein in distilled water(It is not recommended to reconstitute to a concentration<100 μg/mL.)
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Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, pH 7.5.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Ship at 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
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- MMP2 (Matrix Metalloproteinase 2 (MMP2))
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Alternative Name
- MMP-2
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Background
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Synonyms: 72 kDa Type IV Collagenase, 72 kDa Gelatinase, Gelatinase A, Matrix Metalloproteinase-2, MMP-2, TBE-1, MMP2, CLG4A
Description: Recombinant human MMP-2 is produced by the mammalian system, with the target gene encoding Ala30-Cys660 expressed with 6x His-tag at the C-terminus.
Background: 72 kDa type IV collagenase also known as matrix metalloproteinase-2 (MMP-2) and gelatinase A is an enzyme that in humans is encoded by the MMP2 gene.The MMP2 gene is located on chromosome 16 at position 12.2.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix (ECM) in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response.
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UniProt
- P08253
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Pathways
- Activation of Innate immune Response
Target
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