ACVA Protein
Quick Overview for ACVA Protein (ABIN7849716)
Target
See all ACVA ProteinsProtein Type
Origin
Source
Application
Purity
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Purpose
- Recombinant Human / Mouse/ Rat Activin A Protein
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- <0.01EU/μg by LAL test
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Activin A (ACVA) (AA 311-426) (Active) protein
ACVA Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Activin A (ACVA) (AA 21-426) (Active) protein (His tag)ACVA Origin: Human Host: Mammalian Cells Recombinant >90 % as determined by SDS-PAGE. SDS, WB, Imm, ELISA, AcA Active
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Dissolve the lyophilized protein in distilled water(It is not recommended to reconstitute to a concentration<100 μg/mL.)
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Buffer
- Lyophilized from a 0.2 μm filtered solution of 4 mM HCl,4 % Mannitol.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Ship at 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
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- ACVA (Activin A (ACVA))
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Alternative Name
- Activin A
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Background
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Synonyms: Activin beta A chain,EDF,FRP,INHBA,Inhibin Beta A,Inhibin beta A chain,Inhibin β-A,inhibin,beta A
Description: Recombinant human Activin A is produced by the mammalian system, with the target gene encoding Gly311-Ser426 expressed.
Background: Activin A is a homodimer of 14 kDa beta-A. Activin A, a cytokine member of the transforming growth factor-beta superfamily, is expressed locally by the mesenchymal component of the hemopoietic microenvironment. Its expression is regulated on the mRNA level by different cytokines, and the biological activity of the protein is tightly controlled by several inhibitory molecules. Inhibins and activins are members of the transforming growth factor beta superfamily and are known to modulate the growth and differentiation of several cell types. Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
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UniProt
- P08476
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Pathways
- Hormone Transport, Peptide Hormone Metabolism
Target
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