WFDC2 Protein

Catalog No. ABIN7849738

This Recombinant WFDC2 protein is produced in Yeast (Pichia pastoris).

Quick Overview for WFDC2 Protein (ABIN7849738)

Target: WFDC2 (WAP Four-Disulfide Core Domain 2 (WFDC2))

Protein Type: Recombinant

Origin: Human

Source: Yeast (Pichia pastoris)

Application: ELISA, SDS-PAGE (SDS)

Purity: >95 % by SDS-PAGE

Product Details

Purpose: Recombinant Human Epididymis Protein 4, HE4 Protein

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Tris-HCL ( pH 7.4±0.2) with 0.2 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Ship at 4°C. Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.

Target Details

Target: WFDC2 (WAP Four-Disulfide Core Domain 2 (WFDC2))

Alternative Name: HE4

Background:

Synonyms: Human epididymis protein 4, HE4, WAP four-disulfide core domain protein 2, WFDC2

Description: Recombinant human HE4 protein.

Background: WAP four-disulfide core domain protein 2,also known as Human Epididymis Protein 4 (HE4) is a protein that in humans is encoded by the WFDC2 gene. This gene is amplified in ovarian carcinomas, whereas its expression in normal tissues, including ovary, is low. Although the function of the HE4 protein is unknown,it is a member of a family of stable 4-disulfide core proteins that are secreted at high levels.HE4 is a secreted glycoprotein that is overexpressed by serous and endometrioid EOCs(epithelial ovarian carcinomas). Its expression in cortical inclusion cysts suggests that formation of Mullerian epithelium is a prerequisite step in the development of some types ofEOCs.