Annexin V Protein (His tag)

Catalog No. ABIN7884280

This Recombinant Annexin V protein is produced in Escherichia coli (E. coli).

Quick Overview for Annexin V Protein (His tag) (ABIN7884280)

Target: Annexin V (ANXA5) (Annexin A5 (ANXA5))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: Western Blotting (WB)

Purity: >98 %

Product Details

Purification tag / Conjugate: This Annexin V protein is labelled with His tag.

Purpose: Annexin V, Human

Sequence: MAQVLRGTVT DFPGFDERAD AETLRKAMKG LGTDEESILT LLTSRSNAQR QEISAAFKTL FGRDLLDDLK SELTGKFEKL IVALMKPSRL YDAY ELKHALKGAG TNEKVLTEII ASRTPEELRA IKQVYEEEYG SSLEDDVVGD TSGYYQRMLV VLLQANRDPD AGIDEAQVEQ DAQALFQAGE LKW GTDEEKFITI FGTRSVSHLR KVFDKYMTIS GFQIEETIDR ETSGNLEQLL LAVVKSIRSI PAYLAETLYY AMKGAGTDDH TLIRVMVSRS EIDLFNI RKEFRKNFAT SLYSMIKGDT SGDYKKALLL LCGEDD with polyhistid ine tag at the C-terminus

Endotoxin Level: <0.1 EU per 1 μg protein

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: dissolve in sterile H2O

Buffer: PBS, pH 7.4

Storage: -20 °C

Storage Comment: -20°C

Target Details

Target: Annexin V (ANXA5) (Annexin A5 (ANXA5))

Alternative Name: Annexin V

Background: Annexin V is a cellular protein in the annexin group. In flow experiment, annexin V is commonly used to detect apoptotic cells by its ability to bind to phosphatidylserine, a marker of apoptosis when it is on the outer leaflet of the plasma membrane. Annexin V has been proposed to play a role in the inhibition of blood coagulation by competing for phosphatidylserine binding sites with prothrombin and also to inhibit the activity of phospholipase A1.

Molecular Weight: 36kDa

Gene ID: 308

NCBI Accession: NP_001145

UniProt: P08758

Pathways: Apoptosis