LTA Protein (His tag)
Quick Overview for LTA Protein (His tag) (ABIN7884535)
Target
See all LTA ProteinsProtein Type
Biological Activity
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This LTA protein is labelled with His tag.
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Purpose
- TNF beta (Tumor necrosis factor-β), Human
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Sequence
- LPGVGLTPSA AQTARQHPKM HLAHSTLKPA AHLIGDPSKQ NSLLWRANTD RAFLQDGFSL SNNSLLVPTS GIYFVYSQVV FSGKAYSPKA TS SPLYLAHEVQ LFSSQYPFHV PLLSSQKMVY PGLQEPWLHS MYHGAAFQLT QGDQLSTHTD GIPHLVLSPS TVFFGAFAL with polyhistid ine tag at the N-terminus
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Endotoxin Level
- <0.1 EU per 1 μg protein
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Biological Activity Comment
- >3.3 x 108 IU/mg
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Lymphotoxin-alpha (LTA) (AA 58-205) protein (His-DYKDDDDK-Strep II Tag)
LTA Origin: Human Host: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
Lymphotoxin-alpha (LTA) (Active) proteinLTA Origin: Chemical Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Lymphotoxin-alpha (LTA) (AA 1-205) protein (GST tag)LTA Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Lymphotoxin-alpha (LTA) (AA 35-205) protein (His tag)LTA Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Lymphotoxin-alpha (LTA) (AA 34-202) protein (His tag)LTA Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Lymphotoxin-alpha (LTA) (AA 35-205) (Active) protein (His tag)LTA Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 90 % SDS, AcA Active
Lymphotoxin-alpha (LTA) (AA 35-205) (Active) protein (His tag)LTA Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS, AcA Active
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- dissolve in sterile H2O
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Buffer
- pH 3.5
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Storage
- -20 °C
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Storage Comment
- -20°C
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- LTA (Lymphotoxin-alpha (LTA))
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Alternative Name
- TNF beta
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Background
- TNF-β works as a potential mediator in the inflammatory and immune process. It a component of the TNF family of ligands, and signals through TNFR1 and TNFR2. TNF-β is secreted by activated T and B lymphocytes, and has similar function to TNF-α. In the same manner as TNF-α, TNF-β is involved in the regulation of various biological processes, including cell proliferation, differentiation, apoptosis, lipid metabolism, coagulation, and neurotransmission. TNF-β is generally released as a soluble polypeptide. In addition, lymphotoxin-β can anchor TNF-β to the cell surface and form heterotrimers in an effective manner. TNF-β is cytotoxic to a wide range of tumor cells.
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Molecular Weight
- 22kDa
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Gene ID
- 4049
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NCBI Accession
- NP_000586
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UniProt
- P01374
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Target
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