LTA Protein
Quick Overview for LTA Protein (ABIN7955919)
Target
See all LTA ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Purpose
- Recombinant Human Tumor Necrosis Factor-beta/TNFSF1
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Sequence
- LPGVGLTPSA AQTARQHPKM HLAHSTLKPA AHLIGDPSKQ NSLLWRANTD RAFLQDGFSL SNNSLLVPTS GIYFVYSQVV FSGKAYSPKA TSSPLYLAHE VQLFSSQYPF HVPLLSSQKM VYPGLQEPWL HSMYHGAAFQ LTQGDQLSTH TDGIPHLVLS PSTVFFGAFA L
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- Less than 0.1 EU/ug of rHuTNF-beta/TNFSF1 as determined by LAL method.
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Biological Activity Comment
- Fully biologically active when compared to standard. The ED50 as determined by a cytotoxicity assay using murine L929 cells is less than 5 pg/ml, corresponding to a specific activity of > 2.0 x108 IU/mg in the presence of actinomycin D.
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Comment
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Approximately 18.7 kDa, a single non-glycosylated polypeptide chain containing 171 amino acids.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4, with 0.02 % Tween-20.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
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Expiry Date
- 12 months
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- LTA (Lymphotoxin-alpha (LTA))
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Alternative Name
- Tumor Necrosis Factor-beta
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Molecular Weight
- 18.7 kDa
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Target
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