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LTA Protein

This Recombinant LTA protein is produced in Escherichia coli (E. coli).
Catalog No. ABIN7955919
$1,013.10
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Quick Overview for LTA Protein (ABIN7955919)

Target

See all LTA Proteins
LTA (Lymphotoxin-alpha (LTA))

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 18
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Human

Source

  • 31
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Escherichia coli (E. coli)

Purity

> 96 % by SDS-PAGE and HPLC analyses.
  • Purpose

    Recombinant Human Tumor Necrosis Factor-beta/TNFSF1

    Sequence

    LPGVGLTPSA AQTARQHPKM HLAHSTLKPA AHLIGDPSKQ NSLLWRANTD RAFLQDGFSL SNNSLLVPTS GIYFVYSQVV FSGKAYSPKA TSSPLYLAHE VQLFSSQYPF HVPLLSSQKM VYPGLQEPWL HSMYHGAAFQ LTQGDQLSTH TDGIPHLVLS PSTVFFGAFA L

    Sterility

    0.2 μm filtered

    Endotoxin Level

    Less than 0.1 EU/ug of rHuTNF-beta/TNFSF1 as determined by LAL method.

    Biological Activity Comment

    Fully biologically active when compared to standard. The ED50 as determined by a cytotoxicity assay using murine L929 cells is less than 5 pg/ml, corresponding to a specific activity of > 2.0 x108 IU/mg in the presence of actinomycin D.
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  • Comment

    Approximately 18.7 kDa, a single non-glycosylated polypeptide chain containing 171 amino acids.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4, with 0.02 % Tween-20.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.

    Expiry Date

    12 months
  • Target

    LTA (Lymphotoxin-alpha (LTA))

    Alternative Name

    Tumor Necrosis Factor-beta

    Molecular Weight

    18.7 kDa

    Pathways

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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