IL36A/IL1F6 Protein
Quick Overview for IL36A/IL1F6 Protein (ABIN7937285)
Target
See all IL36A/IL1F6 (IL1F6) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Purpose
- Recombinant Murine Interleukin-36 alpha, 153a.a.
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Sequence
- RAASPSLRHV QDLSSRVWIL QNNILTAVPR KEQTVPVTIT LLPCQYLDTL ETNRGDPTYM GVQRPMSCLF CTKDGEQPVL QLGEGNIMEM YNKKEPVKAS LFYHKKSGTT STFESAAFPG WFIAVCSKGS CPLILTQELG EIFITDFEMI VVH
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- Less than 1 EU/ug of rMuIL-36alpha, 153a.a. as determined by LAL method.
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Biological Activity Comment
- Fully biologically active when compared to standard. The ED50 as determined by inducing IL-6 secretion in murine NIH/3T3 cells is less than 25 ng/ml, corresponding to a specific activity of > 4.0 x104 IU/mg.
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Comment
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Approximately 17.1kDa, a single non-glycosylated polypeptide chain containing 153 amino acids.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from a 0.2 um filtered concentrated solution in PBS, 1 mM DTT, 3 % trehalose.
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Preservative
- Dithiothreitol (DTT)
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Precaution of Use
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
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Expiry Date
- 12 months
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- IL36A/IL1F6 (IL1F6) (Interleukin 1 Family, Member 6 (IL1F6))
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Alternative Name
- Interleukin-36 alpha
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Pathways
- Cancer Immune Checkpoints
Target
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