Angiostatin Protein (ANG)

Catalog No. ABIN7937402

This Recombinant Angiostatin protein is produced in Escherichia coli (E. coli).

Quick Overview for Angiostatin Protein (ANG) (ABIN7937402)

Target: Angiostatin (ANG)

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 95 % by SDS-PAGE and HPLC analyses.

Product Details

Purpose: Recombinant Human Angiostatin

Sequence: VYLSECKTGN GKNYRGTMSK TKNGITCQKW SSTSPHRPRF SPATHPSEGL EENYCRNPDN DPQGPWCYTT DPEKRYDYCD ILECEEECMH CSGENYDGKI SKTMSGLECQ AWDSQSPHAH GYIPSKFPNK NLKKNYCRNP DRELRPWCFT TDPNKRWELC DIPRCTTPPP SSGPTYQCLK GTGENYRGNV AVTVSGHTCQ HWSAQTPHTH NRTPENFPCK NLDENYCRNP DGKRAPWCHT TNSQVRWEYC KIPSCDSSP

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 1 EU/ug of rHuAngiostatin as determined by LAL method.

Biological Activity Comment: Fully biologically active when compared to standard. The specific activity determined by an assay on anti-proliferation and anti-migration using endothelial cells in vitro and anti-angiogenesis in vivo is 5.5 x10⁵ IU/mg.

Application Details

Comment:

Approximately 29.7 KDa, a single non-glycosylated polypeptide chain containing 259 amino acids.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from a 0.2 um filtered concentrated solution in 20 mM NaAc, pH 5.5, 4 % mannitol.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Expiry Date: 12 months

Target Details

Target: Angiostatin (ANG)

Alternative Name: Angiostatin

Gene ID: 5340

UniProt: P00747

Pathways: Lipid Metabolism