14-3-3 eta Protein (YWHAH)

Catalog No. ABIN7938560

Recombinant 14-3-3 eta protein expressed in Escherichia coli (E. coli).

Quick Overview for 14-3-3 eta Protein (YWHAH) (ABIN7938560)

Target: 14-3-3 eta (YWHAH)

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)

Product Details

Purpose: Recombinant YWHAH protein

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Recombinant YWHAH protein is supplied in 25 mM Tris pH 8.0, 300 mM NaCl, 20 % glycerol, 0.5 mM TCEP.

Handling Advice: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Storage: -80 °C

Storage Comment: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Target Details

Target: 14-3-3 eta (YWHAH)

Alternative Name: YWHAH

Background:

Protein Background: YWHAH (14-3-3 protein eta) is a adapter protein. Implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.

Short Description: Recombinant YWHAH protein that includes full length of human YWHAH protein (accession number NP_003396.1) was expressed in E. coli and contains an N-terminal His tag with a molecular weight of 30.38 kDa. The purity of the protein is ≥ 95 % by SDS-PAGE.

Aliases: 14-3-3 protein eta, YWHA1, Protein AS1

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, C21-Steroid Hormone Metabolic Process, Myometrial Relaxation and Contraction