Calmodulin 1 Protein (CALM1)
Quick Overview for Calmodulin 1 Protein (CALM1) (ABIN7938674)
Target
See all Calmodulin 1 (CALM1) ProteinsProtein Type
Origin
Source
Application
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Purpose
- Recombinant Calmodulin-1 protein
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Calmodulin 1 (CALM1) (AA 2-149) protein (His-IF2DI Tag)
CALM1 Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Calmodulin 1 (CALM1) protein (Myc-DYKDDDDK Tag)CALM1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Recombinant Calmodulin-1 protein is supplied in 25 mM Tris pH 8.0, 300 mM NaCl, 20 % glycerol, 0.5 mM TCEP.
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Handling Advice
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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Storage
- -80 °C
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Storage Comment
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- Calmodulin 1 (CALM1)
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Alternative Name
- Calmodulin-1
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Background
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Protein Background: Calmodulin acts as part of a calcium signal transduction pathway by mediating the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding. Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases, such as myosin light-chain kinases and calmodulin-dependent protein kinase type II (CaMK2), and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis.
Short Description: Recombinant Calmodulin-1 protein that includes full length of human Calmodulin-1 protein (accession number NP_001316851.1) was expressed in E. coli and contains an N-terminal His tag with a molecular weight of 19 kDa. The purity of the protein is ≥ 85 % by SDS-PAGE.
Aliases: DD132, PHKD1, CAMI, PHKD, Phosphorylase Kinase Delta,CAMII, CPVT4, CAM, CALML2, LQT14
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Pathways
- cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Phototransduction, BCR Signaling
Target
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