CHD3 Protein

Catalog No. ABIN7938711

This Recombinant CHD3 protein is expressed in Baculovirus infected Insect Cells.

Quick Overview for CHD3 Protein (ABIN7938711)

Target: CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))

Protein Type: Recombinant

Origin: Human

Source: Baculovirus infected Insect Cells

Application: Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)

Product Details

Purpose: Recombinant CHD3 protein

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Recombinant CHD3 protein is supplied in 25 mM HEPES-NaOH pH 7.5, 300 mM NaCl, 10 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.

Handling Advice: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Storage: -80 °C

Storage Comment: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Target Details

Target: CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))

Alternative Name: CHD3

Background:

Protein Background: CHD3 (Chromodomain Helicase DNA Binding Protein 3) is a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/ NuRD complex which participates in the remodeling of chromatin by deacetylating histones and is required for anchoring centrosomal pericentrin in both interphase and mitosis, for spindle organization and centrosome integrity. Diseases associated with CHD3 include Snijders Blok-Campeau Syndrome and Agenesis Of Corpus Callosum, Cardiac, Ocular, And Genital Syndrome.

Short Description: Recombinant CHD3 protein was expressed in baculovirus expression system as the full length protein (accession number NP_005843.2) with a N-terminal FLAG tag. The molecular weight of the protein is 224 kDa.

Aliases: Chromodomain helicase DNA binding protein 3