CHD6 Protein (AA 288-959)

Catalog No. ABIN7938716

Recombinant CHD6 protein expressed in Baculovirus infected Insect Cells.

Quick Overview for CHD6 Protein (AA 288-959) (ABIN7938716)

Target: CHD6 (Chromodomain Helicase DNA Binding Protein 6 (CHD6))

Protein Type: Recombinant

Origin: Human

Source: Baculovirus infected Insect Cells

Application: Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)

Product Details

Protein Characteristics: AA 288-959

Purpose: Recombinant CHD6 (288-959) protein

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Recombinant CHD6 (288-959) protein is supplied in 25 mM HEPES pH 7.5, 300 mM NaCl, 20 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.

Handling Advice: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Storage: -80 °C

Storage Comment: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Target Details

Target: CHD6 (Chromodomain Helicase DNA Binding Protein 6 (CHD6))

Alternative Name: CHD6

Background:

Protein Background: CHD6 is a DNA-dependent ATPase that plays a role in chromatin remodeling. Regulates transcription by disrupting nucleosomes in a largely non-sliding manner which strongly increases the accessibility of chromatin. Activates transcription of specific genes in response to oxidative stress through interaction with NFE2L2. Activates transcription of specific genes in response to oxidative stress through interaction with NFE2L2.

Short Description: Recombinant CHD6 (288-959) protein that includes amino acids 288-959 of human CHD6 protein (accession number NP_115597.3) was expressed in a baculovirus expression system and contains an N-terminal FLAG Tag. The molecular weight of the protein is 79.55 kDa.

Pathways: Chromatin Binding