DDX5 Protein

Catalog No. ABIN7938753

This Recombinant DDX5 protein is expressed in Baculovirus infected Insect Cells.

Quick Overview for DDX5 Protein (ABIN7938753)

Target: DDX5 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5))

Protein Type: Recombinant

Origin: Human

Source: Baculovirus infected Insect Cells

Application: Functional Studies (Func), Screening Assay (ScA), Activity Assay (AcA)

Product Details

Purpose: Recombinant DDX5 protein

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Recombinant DDX5 protein is supplied in 25 mM HEPES pH 7.5, 300 mM NaCl, 20 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.

Handling Advice: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Storage: -80 °C

Storage Comment: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Target Details

Target: DDX5 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5))

Alternative Name: DDX5

Background:

Protein Background: DDX5 (Probable ATP-dependent RNA helicase DDX5) encodes a member of the DEAD box family of RNA helicases that are involved in a variety of cellular processes because of its role as an adaptor molecule, promoting interactions with many other factors. This protein is involved in pathways that include the alteration of RNA structures, plays a role as a coregulator of transcription, a regulator of splicing, and in the processing of small noncoding RNAs. Members of this family contain nine conserved motifs, including the conserved Asp-Glu-Ala-Asp (DEAD) motif, important to ATP binding and hydrolysis as well as RNA binding and unwinding activities. Dysregulation of this gene may play a role in cancer development. Alternative splicing results in multiple transcript variants.

Short Description: Recombinant DDX5 protein was expressed in a baculovirus expression system as the full length protein (accession number NP_004387.1) with an N-terminal FLAG tag. The molecular weight of DDX5 is 70.42 kDa.

Aliases: Probable ATP-dependent RNA helicase, G17P1, HLR1, P68, DEAD Box Proteins

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Response to DNA Damage Stimulus