GSG2 Protein (AA 470-798)

Catalog No. ABIN7938857

Recombinant GSG2 protein expressed in Baculovirus infected Insect Cells.

Quick Overview for GSG2 Protein (AA 470-798) (ABIN7938857)

Target: GSG2 (Germ Cell Associated 2 (Haspin) (GSG2))

Protein Type: Recombinant

Origin: Human

Source: Baculovirus infected Insect Cells

Application: Functional Studies (Func), Activity Assay (AcA), Screening Assay (ScA)

Product Details

Protein Characteristics: AA 470-798

Purpose: Recombinant GSG2 (470-798) protein

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Recombinant GSG2 (470-798) / HASPIN protein is supplied in 25 mM HEPES-NaOH pH 7.5, 300 mM NaCl, 10 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.

Handling Advice: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Storage: -80 °C

Storage Comment: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Target Details

Target: GSG2 (Germ Cell Associated 2 (Haspin) (GSG2))

Alternative Name: GSG2

Background:

Protein Background: HASPIN (Histone H3 Associated Protein Kinase) is a serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. It may act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle.

Short Description: Recombinant GSG2 (470-798) / HASPIN protein that includes amino acids 470-798 of human GSG2 protein (accession number NP_114171.2) was expressed in a baculovirus expression system, and contains an N-terminal FLAG tag. The molecular weight of the protein is 38.7 kDa

Aliases: Histone H3 Associated Protein Kinase