PDGFRB Protein (AA 557-1106)
Quick Overview for PDGFRB Protein (AA 557-1106) (ABIN7939425)
Target
See all PDGFRB ProteinsProtein Type
Origin
Source
Application
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Protein Characteristics
- AA 557-1106
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Purpose
- Recombinant PDGFRB (557-1106) protein
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Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 33-531) (Active) protein (His tag)
PDGFRB Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 33-530) (Active) protein (Biotin,His-Avi Tag)PDGFRB Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 33-530) (Active) protein (His-Avi Tag)PDGFRB Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 33-133) protein (GST tag)PDGFRB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Platelet Derived Growth Factor Receptor beta (PDGFRB) (Active) protein (Fc Tag)PDGFRB Origin: Rat Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
Platelet Derived Growth Factor Receptor beta (PDGFRB) (Active) protein (His tag)PDGFRB Origin: Rat Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 33-532) protein (hIgG-His-tag)PDGFRB Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 90 % SDS
Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 33-532) protein (His tag)PDGFRB Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Recombinant PDGFRB (557-1106) protein is supplied in 25 mM HEPES-NaOH pH 7.5, 300 mM NaCl, 10 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.
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Handling Advice
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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Storage
- -80 °C
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Storage Comment
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
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Alternative Name
- PDGFRB
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Background
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Protein Background: PDGFRB (Platelet Derived Growth Factor Receptor Beta), a tyrosine-protein kinase that acts as cell surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, PDGFRB plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration and plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. PDGFRB plays a role in the migration of vascular smooth muscle cells and the formation of neointima at vascular injury sites.
Short Description: Recombinant PDGFRB (557-1106) protein that includes amino acids 557-1106 of human PDGFRB protein (accession number NP_002600.1) was expressed in a baculovirus expression system, and contains an N-terminal FLAG tag. The molecular weight of the protein is 63 kDa.
Aliases: Platelet Derived Growth Factor Receptor Beta
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Pathways
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
Target
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