PKC beta Protein
Quick Overview for PKC beta Protein (ABIN7939465)
Target
See all PKC beta (PRKCB) ProteinsProtein Type
Origin
Source
Application
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Purpose
- Recombinant PRKCB protein
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Protein Kinase C, beta (PRKCB) (AA 1-671) protein (GST tag)
PRKCB Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Protein Kinase C, beta (PRKCB) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)PRKCB Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Protein Kinase C, beta (PRKCB) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)PRKCB Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Recombinant PRKCB protein is supplied in 25 mM HEPES pH 7.5, 300 mM NaCl, 20 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.
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Handling Advice
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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Storage
- -80 °C
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Storage Comment
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- PKC beta (PRKCB) (Protein Kinase C, beta (PRKCB))
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Alternative Name
- PRKCB
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Background
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Protein Background: PRKCB (Protein kinase C beta type), also known as PKC-beta, PKCB, PKCbeta, PKCI(2), PRKCB1 and PRKCB2. PRKCB is a calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase involved in various cellular processes such as regulation of the B-cell receptor (BCR) signalosome, oxidative stress-induced apoptosis, androgen receptor-dependent transcription regulation, insulin signaling and endothelial cells proliferation.
Short Description: Recombinant PRKCB protein was expressed in a baculovirus expression system as the full length protein (accession number NP_002729.2) with an N-terminal FLAG tag. The molecular weight of the protein is 78.3 kDa.
Aliases: Protein kinase C beta type, PKC-beta, PKCB, PKCbeta, PKCI(2), PRKCB1, PRKCB2
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Pathways
- WNT Signaling, TCR Signaling, Thyroid Hormone Synthesis, Nuclear Hormone Receptor Binding, Chromatin Binding, Myometrial Relaxation and Contraction, VEGF Signaling, Unfolded Protein Response, BCR Signaling
Target
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