PCMTD2 Protein
Quick Overview for PCMTD2 Protein (ABIN7939488)
Target
Protein Type
Origin
Source
Application
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Purpose
- Recombinant PCMTD2 protein
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Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase Domain Containing 2 (PCMTD2) (AA 1-361) protein (GST tag)
PCMTD2 Origin: Human Host: Wheat germ Recombinant ELISA, AP, AA, WB
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Recombinant PCMTD2 protein is supplied in 25 mM Tris-HCl pH 8.0, 300 mM NaCl, 10 % glycerol and 0.5 mM TCEP.
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Handling Advice
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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Storage
- -80 °C
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Storage Comment
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- PCMTD2 (Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase Domain Containing 2 (PCMTD2))
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Alternative Name
- PCMTD2
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Background
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Protein Background: PCMTD2(Protein-L-isoaspartate O-methyltransferase domain-containing protein 2) may act as a substrate recognition component of an ECS (Elongin BC-CUL5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. May bind to the methyltransferase cofactor S-adenosylmethionine (AdoMet) via the N-terminal AdoMet binding motif, but probably does not display methyltransferase activity.
Short Description: Recombinant PCMTD2 protein that includes full length of human PCMTD2 protein (accession number NP_060727.2) was expressed was expressed in E. coli cells with an N-terminal GST tag. The molecular weight of the protein is 67.9 kDa.
Aliases: Protein-L-isoaspartate O-methyltransferase domain-containing protein 2, C20orf36, FLJ10883
Target
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