STK10-A Protein (AA 1-348)
Quick Overview for STK10-A Protein (AA 1-348) (ABIN7939542)
Target
See all STK10-A ProteinsProtein Type
Origin
Source
Application
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Protein Characteristics
- AA 1-348
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Purpose
- Recombinant STK10 / LOK (1-348) protein
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Serine/threonine Kinase 10 (STK10-A) (AA 12-144) protein (GST tag)
STK10-A Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Serine/threonine Kinase 10 (STK10-A) (Active) protein (His tag)STK10-A Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE. Active
Serine/threonine Kinase 10 (STK10-A) protein (Myc-DYKDDDDK Tag)STK10-A Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Recombinant STK10 / LOK (1-348) protein is supplied in 25 mM HEPESNaOH pH 7.5, 300 mM NaCl, 10 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.
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Handling Advice
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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Storage
- -80 °C
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Storage Comment
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- STK10-A (Serine/threonine Kinase 10 (STK10-A))
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Alternative Name
- STK10 & LOK
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Background
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Protein Background: STK10 (Serine/Threonine Kinase 10) is a serine/threonine-protein kinase involved in regulation of lymphocyte migration. STK10 phosphorylates MSN and involved in regulation of lymphocyte migration by mediating phosphorylation of ERM proteins such as MSN. It acts as a negative regulator of MAP3K1/MEKK1 and may also act as a cell cycle regulator by acting as a polo kinase kinase. Diseases associated with STK10 include Testicular Germ Cell Tumor.
Short Description: Recombinant STK10 / LOK (1-348) protein that includes amino acids 1-348 of human LOK protein (accession number NP_005981.3) was expressed in a baculovirus expression system, and contains an N-terminal FLAG tag. The molecular weight of the protein is 40.4 kDa
Aliases: Serine / threonine kinase 10
Target
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