SUMO3 Protein
Quick Overview for SUMO3 Protein (ABIN7939591)
Target
See all SUMO3 ProteinsProtein Type
Origin
Source
Application
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Purpose
- Recombinant SUMO3 protein - biotinylated
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Recombinant SUMO3 protein - biotinylated is supplied in 25 mM Tris pH 8.0, 300 mM NaCl, 20 % glycerol, 0.5 mM TCEP.
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Handling Advice
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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Storage
- -80 °C
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Storage Comment
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- SUMO3 (Small Ubiquitin Related Modifier 3 (SUMO3))
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Alternative Name
- SUMO3
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Background
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Protein Background: SUMO3 (Small ubiquitin-related modifier 3) is a ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. Plays a role in the regulation of sumoylation status of SETX.
Short Description: Recombinant SUMO3 protein - biotinylated that includes full length of human SUMO3 protein (accession number NP_008867.2) was expressed in E. coli and contains an N-terminal His & Avi tag with a molecular weight of 15.89 kDa. This protein has been modified by biotin in vivo. The purity of the protein is ≥ 90 % by SDS-PAGE.
Aliases: SMT3A, SMT3H1, Small ubiquitin related modifiers, Smt3B
Target
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