SOX9 Protein

Catalog No. ABIN7939607

Recombinant SOX9 protein expressed in Baculovirus infected Insect Cells.

Quick Overview for SOX9 Protein (ABIN7939607)

Target: SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

Protein Type: Recombinant

Origin: Human

Source: Baculovirus infected Insect Cells

Application: Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)

Product Details

Purpose: Recombinant SOX9 protein

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Recombinant SOX9 protein is supplied in 25 mM HEPES pH 7.5, 300 mM NaCl, 20 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.

Handling Advice: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Storage: -80 °C

Storage Comment: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Target Details

Target: SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

Alternative Name: SOX9

Background:

Protein Background: SOX9 is a transcription factor that plays a key role in chondrocytes differentiation and skeletal development. Specifically binds the 5'-ACAAAG-3' DNA motif present in enhancers and super-enhancers and promotes expression of genes important for chondrogenesis, including cartilage matrix protein-coding genes COL2A1, COL4A2, COL9A1, COL11A2 and ACAN, SOX5 and SOX6.

Short Description: Recombinant SOX9 protein was expressed in a baculovirus expression system as the full length protein (accession number NP_000337.1) with an N-terminal FLAG tag. The molecular weight of SOX9 is 57.41 kDa.

Aliases: SRA1, Transcription Factor SOX-9, CMPD1, CMD1, SRXY10, TESCO, TES

Pathways: EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development