UBE2C Protein
Quick Overview for UBE2C Protein (ABIN7939679)
Target
See all UBE2C ProteinsProtein Type
Origin
Source
Application
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Purpose
- Recombinant UBE2C protein
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Ubiquitin-Conjugating Enzyme E2C (UBE2C) (AA 1-179) protein (GST tag)
UBE2C Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Ubiquitin-Conjugating Enzyme E2C (UBE2C) (AA 1-179) protein (His-IF2DI Tag)UBE2C Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Ubiquitin-Conjugating Enzyme E2C (UBE2C) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)UBE2C Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Ubiquitin-Conjugating Enzyme E2C (UBE2C) (Transcript Variant 4) protein (Myc-DYKDDDDK Tag)UBE2C Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Ubiquitin-Conjugating Enzyme E2C (UBE2C) (Transcript Variant 5) protein (Myc-DYKDDDDK Tag)UBE2C Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Recombinant UBE2C protein is supplied in 25 mM Tris 8.0, 300 mM NaCl, 20 % glycerol, 0.5 mM TCEP.
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- UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))
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Alternative Name
- UBE2C
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Background
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Protein Background: UBE2C (Ubiquitin-conjugating enzyme E2 C) also known as dJ447F3.2 and UBCH10. UBE2C is a member of the E2 ubiquitin-conjugating enzyme family which is required for post-replicative DNA damage repair and plays an important role in various cellular processes. UBE2C can accept ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit.
Short Description: Recombinant UBE2C protein that includes full length of human UBE2C protein (accession number NP_008950.1) was expressed in E. coli and contains an N-terminal His tag with a molecular weight of 21.82 kDa. The purity of the protein is ≥ 90 % by SDS-PAGE.
Aliases: Ubiquitin conjugating enzyme E2 C, dj447F3.2, UBCH10
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Pathways
- Ubiquitin Proteasome Pathway
Target
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