CD74 Protein (AA 73-296)
Quick Overview for CD74 Protein (AA 73-296) (ABIN8128058)
Target
See all CD74 ProteinsProtein Type
Biological Activity
Origin
Source
Application
Purity
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Protein Characteristics
- AA 73-296
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Purpose
- Active Cluster Of Differentiation 74 (CD74)
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Sequence
- Gln73-Met296
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HLA-DR-gamma (CD74) (AA 56-279) (Active) protein (His tag)
CD74 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
HLA-DR-gamma (CD74) (AA 1-160) protein (GST tag)CD74 Origin: Human Host: Wheat germ Recombinant AP, AA, ELISA, WB
HLA-DR-gamma (CD74) (AA 99-330) protein (Fc Tag)CD74 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
HLA-DR-gamma (CD74) (AA 73-232) protein (His tag)CD74 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
HLA-DR-gamma (CD74) (AA 56-215) protein (mFc-His Tag)CD74 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
HLA-DR-gamma (CD74) (AA 56-215) protein (His tag)CD74 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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STABILITY: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Isoelectric Point: 7.9
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute in 10 mM PBS ( pH 7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
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Buffer
- PBS, pH 7.4, containing 0.01 % SKL, 1 mM DTT, 5 % Trehalose and Proclin300.
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Preservative
- Dithiothreitol (DTT), ProClin
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Precaution of Use
- This product contains ProClin and Dithiothreitol (DTT): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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Storage
- 4 °C,-80 °C
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Storage Comment
- Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
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- CD74 (HLA-DR-gamma (CD74))
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Alternative Name
- CD74
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Background
- MHCDG, HLA-DG, HLADG, DHLAG, Ia-GAMMA, HLA class II histocompatibility antigen gamma chain, Ia antigen-associated invariant chain, HLA-DR antigens-associated invariant chain
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Molecular Weight
- 38-50kDa
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UniProt
- P04233
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Pathways
- Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints
Target
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