LAG3 Protein (AA 24-442)
Quick Overview for LAG3 Protein (AA 24-442) (ABIN8128678)
Target
See all LAG3 ProteinsProtein Type
Biological Activity
Origin
Source
Application
Purity
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Protein Characteristics
- AA 24-442
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Purpose
- Active Lymphocyte Activation Gene 3 (LAG3)
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Sequence
- Gly24-Leu442
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Lymphocyte-Activation Gene 3 (LAG3) (AA 23-434) (Active) protein (Biotin,His-Avi Tag)
LAG3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Lymphocyte-Activation Gene 3 (LAG3) (AA 23-450) (Active) protein (hFc Tag)LAG3 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE,> 90 % as determined by HPLC Active
Lymphocyte-Activation Gene 3 (LAG3) (AA 23-450) protein (His tag)LAG3 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Lymphocyte-Activation Gene 3 (LAG3) (AA 23-450) protein (Fc Tag)LAG3 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Lymphocyte-Activation Gene 3 (LAG3) (AA 23-222) protein (His-IF2DI Tag)LAG3 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Lymphocyte-Activation Gene 3 (LAG3) (AA 23-450) protein (His tag)LAG3 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
Lymphocyte-Activation Gene 3 (LAG3) (AA 1-442) protein (His tag)LAG3 Origin: Rat Host: HEK-293 Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
Lymphocyte-Activation Gene 3 (LAG3) (AA 18-449) protein (Fc Tag)LAG3 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Lymphocyte-Activation Gene 3 (LAG3) (AA 1-360) protein (GST tag)LAG3 Origin: Human Host: Wheat germ Recombinant AP, AA, ELISA, WB
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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STABILITY: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Isoelectric Point: 9.2
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute in 20 mM Tris, 150 mM NaCl ( pH 8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
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Buffer
- PBS, pH 7.4, containing 0.01 % SKL, 1 mM DTT, 5 % Trehalose and Proclin300.
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Preservative
- Dithiothreitol (DTT), ProClin
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Precaution of Use
- This product contains ProClin and Dithiothreitol (DTT): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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Storage
- 4 °C,-80 °C
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Storage Comment
- Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
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- LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
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Alternative Name
- Lymphocyte Activation Gene 3
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Background
- CD223, Protein FDC
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Molecular Weight
- 55kDa
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UniProt
- Q5BK54
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
Target
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