Cathepsin G Protein (CTSG)

Catalog No. ABIN934534

Native Cathepsin G protein expressed in Human.

Quick Overview for Cathepsin G Protein (CTSG) (ABIN934534)

Target: Cathepsin G (CTSG)

Protein Type: Native

Biological Activity: Active

Origin: Human

Source: Human

Purity: > 95 % pure

Product Details

Characteristics: Purified native Human Cathepsin G protein
Bioactivity: 2-4 units/mg - One unit of activity is defined as the amount of enzyme that hydrolyzes one micromole of Suc-ala-ala-pro-phe-pNA (1mM) per minute at 25o C in 160 mM Tris-HCl, pH 7.4, with 1.6 M NaCl.
Protein Source: Human neutrophils

Application Details

Application Notes: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with 50 mM CH3COONa, pH 5.5, and with 150 M NaCl.

Buffer: Salt-free lyophilized solid.

Precaution of Use: Donor samples were tested and found to be negative for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C.

Target Details

Target: Cathepsin G (CTSG)

Alternative Name: Cathepsin G

Background: Cathepsin G is an enzymatic protein belonging to the peptidase or protease families. In humans, it is coded by the CTSG gene. This enzyme degrades collagen and proteoglycan and can also cause the release of angiotensin II from angiotensin I or angiotensinogen. It has been implicated in connective tissue diseases such as emphysema and rheumatoid arthritis.
Description: Human neutrophils.

Molecular Weight: 23.5 Da

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones