IL16 Protein
(1 reference)Quick Overview for IL16 Protein (ABIN934622)
Target
See all IL16 ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Sequence
- MPDLNSSTDS AASASAASDV SVESTAEATV CTVTLEKMSA GLGFSLEGGK GSLHGDKPLT INRIFKGAAS EQSETVQPGD EILQLGGTAM QGLTRFEAWN IIKALPDGPV TIVIRRKSLQ SKETTAAGDS
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Characteristics
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Purified recombinant Human IL16 protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract human CD4+ T lymphoytes using a concentration range of 1.0-100.0 ng/mL. -
Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
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Interleukin 16 (IL16) (AA 1-1322) protein (His tag)
custom-made IL16 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Interleukin 16 (IL16) (AA 1-1332) protein (His tag)custom-made IL16 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Interleukin 16 (IL16) (AA 1203-1332) (Active) protein (His tag)IL16 Origin: Human Host: Escherichia coli (E. coli) > 97 % AcA, CC Active
Interleukin 16 (IL16) proteinIL16 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
Interleukin 16 (IL16) (AA 1-454) protein (GST tag)IL16 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 16 (IL16) (AA 502-631) proteinIL16 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90% by SDS-PAGE SDS
Interleukin 16 (IL16) proteinIL16 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant 95,00% SDS
Interleukin 16 (IL16) proteinIL16 Origin: Human Host: Escherichia coli (E. coli) Recombinant 95,00% SDS
Interleukin 16 (IL16) proteinIL16 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant 95,00% SDS
Interleukin 16 (IL16) proteinIL16 Origin: Human Host: Escherichia coli (E. coli) Recombinant 95,00% SDS
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute in water to a concentration of 0.1-1.0 mg/mL.
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Buffer
- Lyophilized from 5 mM Na3PO4, pH 7.6.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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: "IL-16 signaling specifically induces STAT6 activation through CD4." in: Cytokine, Vol. 38, Issue 3, pp. 145-50, (2007) (PubMed).
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: "IL-16 signaling specifically induces STAT6 activation through CD4." in: Cytokine, Vol. 38, Issue 3, pp. 145-50, (2007) (PubMed).
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- IL16 (Interleukin 16 (IL16))
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Alternative Name
- IL16
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Background
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IL16 is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, hIL16 exists predominantly as a noncovalently linked multimer, but that some IL16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL16 also induces expression of IL2 receptor (IL2R) and MHC class II molecules on CD4 + T cells. Human and Mouse IL16 show significant cross-species reactivity.
Alternative Names: IL-16 protein, IL16, IL-16 protein, Interleukin 16 protein, IL 16, Lymphocyte Chemoattractant Factor protein, IL 16 protein, LCF protein, IL-16 -
Molecular Weight
- 13.5 kDa
Target
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