beta-2 Microglobulin Protein

Catalog No. ABIN934771

Native beta-2 Microglobulin protein expressed in Human and has been mentioned in 1 publication.

Quick Overview for beta-2 Microglobulin Protein (ABIN934771)

Target: beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Protein Type: Native

Origin: Human

Source: Human

Purity: > 98 % pure

Product Details

Characteristics: Purified native Human beta 2 Microglobulin protein
Protein Source: Urine of patients with chronic renal tubular proteinuria

Sterility: Filtered

Application Details

Application Notes: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Sterile filtered liquid in 40 mM PBS, pH 7.2, with 150 mMM NaCl, 0 M EDTA sodium salt, and 0.05 % NaN3.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C

Storage Comment: Store at 4 °C.

References

Neethling, Ramakrishna, Keler, Buchli, Woodburn, Weidanz: "Assessing vaccine potency using TCRmimic antibodies." in: Vaccine, Vol. 26, Issue 25, pp. 3092-102, (2008) (PubMed).

Target Details

Target: beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Alternative Name: beta 2 Microglobulin

Background: Beta2 microglobulin also known as B2M is a component of MHC class I molecules, which are present on all nucleated cells (excludes red blood cells). In humans, the B2 microglobulin protein is encoded by the B2M gene.
Description: Urine of patients with chronic renal tubular proteinuria.
Alternative Names: B2M protein, beta chain of mhc class 1 proteins protein, beta Microglobulin-2 protein, beta Microglobulin-2, beta Microglobulin 2, beta 2 Microglobulin, beta Microglobulin 2 protein, Hdcma22p protein, beta 2 microglobulin precursor protein

Pathways: TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process