Myeloperoxidase Protein (MPO)

Catalog No. ABIN934827

This Native Myeloperoxidase protein is expressed in Human.

Quick Overview for Myeloperoxidase Protein (MPO) (ABIN934827)

Target: Myeloperoxidase (MPO)

Protein Type: Native

Biological Activity: Active

Origin: Human

Source: Human

Purity: > 95 % pure

Product Details

Characteristics: Purified native Human MPO protein
Bioactivity: 180-220 units/mg after lyophilization - One unit of activity is defined as the amount of enzyme that will decompose one micromole of hydrogen peroxide per minute at 25o C , pH 6.1. Reaction mixture contains 33 mM sodium phosphate, pH 6.1, 30 mM guaiacol, and 0.0012 % (0.35 mM) hydrogen peroxide.
Protein Source: Human neutrophils

Purification: Affinity chromatography

Application Details

Application Notes: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from 50 mM NaC0 0 2, pH 6.0 with 100 mM NaCl.

Precaution of Use: Donor samples were tested and found to be negative for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C.

Target Details

Target: Myeloperoxidase (MPO)

Alternative Name: MPO

Background: Myeloperoxidase is a heme protein which catalyzes oxidations by hydrogen peroxide, including MPO- chloride mediated killing of microbes and tumor cells, inactivation of hemotactic factors, crosslinking of proteins and inclination of proteins.
Description: Human neutrophils.
Alternative Names: Myeloperoxidase antibody

Molecular Weight: 150 kDa

Pathways: Chromatin Binding