GADD45G Protein (AA 1-159)
Quick Overview for GADD45G Protein (AA 1-159) (ABIN935003)
Target
See all GADD45G ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 1-159
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Sequence
- MTLEELVACD NAAQKMQTVT AAVEELLVAA QRQDRLTVGV YESAKLMNVD PDSVVLCLLA IDEEEEDDIA LQIHFTLIQS FCCDNDINIV RVSGMQRLAQ LLGEPAETQG TTEARDLHCL LVTNPHTDAW KSHGLVEVAS YCEESRGNNQ WVPYISLQER
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Characteristics
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Purified recombinant Human GADD45 G protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher.
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Growth Arrest and DNA-Damage-Inducible, gamma (GADD45G) (AA 1-159) protein (His tag)
custom-made GADD45G Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Growth Arrest and DNA-Damage-Inducible, gamma (GADD45G) (AA 1-159) protein (His tag)custom-made GADD45G Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Growth Arrest and DNA-Damage-Inducible, gamma (GADD45G) (AA 1-159) protein (GST tag)GADD45G Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Growth Arrest and DNA-Damage-Inducible, gamma (GADD45G) (AA 1-159), (full length) protein (His-SUMO Tag)GADD45G Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Growth Arrest and DNA-Damage-Inducible, gamma (GADD45G) protein (Myc-DYKDDDDK Tag)GADD45G Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
- GADD protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Supplied as a liquid in 20 mM Tris-HCl, pH 7.5.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- RT/-20 °C
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Storage Comment
- Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
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- GADD45G (Growth Arrest and DNA-Damage-Inducible, gamma (GADD45G))
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Alternative Name
- GADD45G
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Background
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GADD45G is a member of GADD45 family (GADD45alpha, beta, and gamma) that are nuclear proteins with interact with various proteins implicated in stress responses and cell-cycle-related proteins. The function of GADD45 proteins is involved in growth-regulatory mechanisms and apoptosis. GADD45G protein responds to environmental stresses by mediating activation of p38/JNK pathway via MTK1/MEKK4 kinase and its transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. Recombinant GADD45G protein was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: GRP17, Growth arrest and DNA damage inducible gamma protein, DDIT2 protein, Growth arrest and DNA-damage-inducible gamma protein, GADD45G protein, Growth arrest and DNA-damage-inducible gamma protein, CR6 protein, Cytokine responsive protein CR6 protein -
Molecular Weight
- 17.8 kDa (160 AA)
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Pathways
- Cell Division Cycle
Target
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