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Ketohexokinase Protein (KHK) (AA 1-298)

This Recombinant Ketohexokinase protein is produced in Escherichia coli (E. coli).
Catalog No. ABIN935075

Quick Overview for Ketohexokinase Protein (KHK) (AA 1-298) (ABIN935075)

Target

See all Ketohexokinase (KHK) Proteins
Ketohexokinase (KHK)

Protein Type

Recombinant

Origin

  • 7
  • 2
  • 1
Human

Source

  • 5
  • 2
  • 1
  • 1
  • 1
Escherichia coli (E. coli)

Application

SDS-PAGE (SDS)

Purity

> 90 % pure
  • Protein Characteristics

    AA 1-298

    Sequence

    MEEKQILCVG LVVLDVISLV DKYPKEDSEI RCLSQRWQRG GNASNSCTIL SLLGAPCAFM GSMAPGHVAD FVLDDLRRYS VDLRYTVFQT TGSVPIATVI INEASGSRTI LYYDRSLPDV SATDFEKVDL TQFKWIHIEG RNASEQVKML QRIDAHNTRQ PPEQKIRVSV EVEKPREELF QLFGYGDVVF VSKDVAKHLG FQSAEEALRG LYGRVRKGAV LVCAWAEEGA DALGPDGKLL HSDAFPPPRV VDTLGAGDTF NASVIFSLSQ GRSVQEALRF GCQVAGKKCG LQGFDGIV

    Characteristics

    Purified recombinant Human Ketohexokinase protein
    Expression System: E.coli
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  • Application Notes

    Ketohexokinase protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Supplied as a liquid in PBS, pH 7.4, containing 10 % glycerol.

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    RT/-20 °C

    Storage Comment

    Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
  • Target

    Ketohexokinase (KHK)

    Alternative Name

    Ketohexokinase

    Background

    Ketohexokinase is an enzyme that catalyzes the phosphorylation of fructose to produce fructose-1-phosphate, leading to consumption of ATP, formation of AMP. This protein initiates first step in the metabolism of dietary fructose and is an important regulator of hepatic glucose metabolism. It is highly found in liver, renal cortex, and small intestine. Its deficiency causes the benign hereditary metabolic disorder essential fructosuria, leading to fructose being excreted in the urine. Recombinant human Ketohexokinase was expressed in E. coli and purified by using conventional chromatography.
    Alternative Names: Hepatic fructokinase protein, EC 2.7.1.3 protein, KHK protein, , Hepatic fructokinase protein, ketohexokinase protein, Ketohexokinase isoform a protein

    Molecular Weight

    32.7 kDa (298 AA)
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