ATF3 Protein (AA 1-181)
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- Target See all ATF3 Proteins
- ATF3 (Activating Transcription Factor 3 (ATF3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-181
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- Sequence
- MMLQHPGQVS ASEVSASAIV PCLSPPGSLV FEDFANLTPF VKEELRFAIQ NKHLCHRMSS ALESVTVSDR PLGVSITKAE VAPEEDERKK RRRERNKIAA AKCRNKKKEK TECLQKESEK LESVNAELKA QIEELKNEKQ HLIYMLNLHR PTCIVRAQNG RTPEDERNLF IQQIKEGTLQ S
- Characteristics
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Purified recombinant ATF3 protein
Expression System: E.coli - Purity
- > 90 % pure
- Top Product
- Discover our top product ATF3 Protein
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Activating Transcription Factor 3 (ATF3) (AA 1-181) protein (GST tag)
ATF3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Activating Transcription Factor 3 (ATF3) (AA 1-90) protein (GST tag)ATF3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Activating Transcription Factor 3 (ATF3) (AA 1-181) protein (Strep Tag)Crystallography grade ATF3 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Activating Transcription Factor 3 (ATF3) (AA 1-181) protein (Strep Tag)Crystallography grade ATF3 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Activating Transcription Factor 3 (ATF3) protein (His tag)ATF3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Activating Transcription Factor 3 (ATF3) protein (GST tag,His tag)ATF3 Origin: Human Host: Insect cells (Sf9) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- ATF3 protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Supplied as a liquid in 20 mM Tris-HCl, pH 8.0, containing 2 M Urea and 20 % glycerol.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- RT/-20 °C
- Storage Comment
- Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
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- Target
- ATF3 (Activating Transcription Factor 3 (ATF3))
- Alternative Name
- ATF3 (ATF3 Products)
- Synonyms
- zgc:55526 Protein, ATF3 Protein, LRG-21 Protein, LRF-1 Protein, LRFI Protein, atf-3 Protein, activating transcription factor 3 Protein, activating transcription factor 3 L homeolog Protein, atf3 Protein, ATF3 Protein, Atf3 Protein, atf3.L Protein
- Background
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ATF3 (activating transcription factor 3) is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription, it is presumed, by sequestering inhibitory co-factors away from the promoter.
Alternative Names: ATF 3, ATF-3 protein, ATF 3 protein, ATF3, ATF-3, Cyclic AMP dependent transcription factor ATF3 protein, ATF3deltaZip3 protein, ATF3deltaZip2 protein, cAMP dependent transcription factor ATF3 protein, ATF3deltaZip2c protein, Cyclic AMP-dependent transcription factor ATF-3 protein - Molecular Weight
- 20.6kDa (181 AA)
- Pathways
- Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response
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