FGF1 Protein

Catalog No. ABIN935130

Product Details

Target: FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Escherichia coli (E. coli)

Characteristics: Purified recombinant Human Acidic Fibroblast Growth Factor
Expression System: E.coli
Bioactivity: < 3 ng/mL for half maximum stimulation of cell proliferation with bovine aortic endothelial cells (BAE cells)

Purification: Affinity chromatography

Purity: > 95 % pure

Application Details

Application Notes: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Supplied in lyophilized form in 100 µL phosphate buffered saline (pH 6), supplemented with 5 mM glutathion.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C in lyophilized form. Following reconstitution aliquot and store at -20 °C for long term storage.

Target Details

Target: FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))

Alternative Name: FGF1 (FGF1 Products)

Synonyms: AFGF Protein, ECGF Protein, ECGF-beta Protein, ECGFA Protein, ECGFB Protein, FGF-1 Protein, FGF-alpha Protein, FGFA Protein, GLIO703 Protein, HBGF-1 Protein, HBGF1 Protein, Fgf1 Protein, FGF1 Protein, aFGF Protein, ecgf Protein, fgfa Protein, ecgfa Protein, ecgfb Protein, fgf-1 Protein, hbgf1 Protein, glio703 Protein, ecgf-beta Protein, fgf-alpha Protein, Dffrx Protein, Fam Protein, Fgf-1 Protein, Fgfa Protein, zgc:136885 Protein, LOC100221393 Protein, fgf1 Protein, zgc:73249 Protein, fibroblast growth factor 1 Protein, fibroblast growth factor 1 L homeolog Protein, fibroblast growth factor 1b Protein, fibroblast growth factor 1a Protein, FGF1 Protein, fgf1.L Protein, fgf1 Protein, Fgf1 Protein, fgf1b Protein, LOC100221393 Protein, fgf1a Protein

Background: This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Three alternatively spliced variants encoding different isoforms have been described.
Alternative Names: FGF 1, FGF1, Acidic Fibroblast Growth Factor, FGF-1 protein, HBGF-1 protein, FGF 1 protein, ACGFB protein, ECGF protein, AFGF protein, FGFA protein, Heparin-binding growth factor 1, FGF-1, ECGFA protein, Prostatropin

Molecular Weight: 20 kDa

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway