Cytokeratin 18 Protein
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- Target See all Cytokeratin 18 (KRT18) Proteins
- Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
- Protein Type
- Native
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Origin
- Cow
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Source
- Cow
- Characteristics
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Purified native Bovine Keratin K18 Protein
Protein Source: Bovine liver - Purity
- > 95 % pure
- Top Product
- Discover our top product KRT18 Protein
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Keratin 18 (KRT18) protein (His tag)
KRT18 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >85 % as determined by reducing SDS-PAGE.
Keratin 18 (KRT18) (AA 1-430) protein (His tag)KRT18 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Keratin 18 (KRT18) (AA 1-430) protein (GST tag)KRT18 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Keratin 18 (KRT18) (AA 2-423) protein (His tag)Crystallography grade KRT18 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- 1 mg/mL
- Buffer
- Supplied in lyophilized form with 30 mM Tris/HCI pH 8, 9 M urea, 2 mM DTT, 2 mM EDTA, 10 mM methylammonium chloride.
- Preservative
- Dithiothreitol (DTT)
- Precaution of Use
- This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 2-8 °C in lyophilized form. Following reconstitution aliquot and store at -20 °C for long term storage.
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- Target
- Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
- Alternative Name
- Keratin K18 (KRT18 Products)
- Synonyms
- CK18 Protein, K18 Protein, Krt1-18 Protein, CYK18 Protein, DreK18 Protein, cb83 Protein, dapk1 Protein, sb:cb83 Protein, wu:fa13f02 Protein, wu:fb36b04 Protein, krt18 Protein, MGC64569 Protein, MGC75922 Protein, KRT18 Protein, CK-18-A Protein, K18-A Protein, NC-11 Protein, cyk18 Protein, k18 Protein, krt18-a Protein, krt18-b Protein, krt18a Protein, xkendob Protein, keratin 18 Protein, keratin 18, type I L homeolog Protein, keratin 18, type I Protein, keratin, type I cytoskeletal 18 Protein, K18, simple type I keratin Protein, Keratin, type I cytoskeletal 18 Protein, keratin 18, type I S homeolog Protein, Krt18 Protein, KRT18 Protein, krt18 Protein, krt18.L Protein, LOC700569 Protein, LOC100136778 Protein, k1c18 Protein, LOC100008885 Protein, krt18.S Protein
- Background
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Keratin 18 is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the most commonly found products of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. Keratin 18 is often used together with keratin 8 and keratin 19 to differentiate cells of epithelial origin from hematopoietic cells in tests that enumerate circulating tumor cells in blood.
Description: Bovine liver.
Alternative Names: Cytokeratin 18 protein, Keratin K 18, Keratin K 18 protein, Keratin K18, Keratin K-18 protein, Keratin K-18, Keratin 18 protein - Molecular Weight
- 45 kDa
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis
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