SAA1 Protein

Catalog No. ABIN935202

This Recombinant SAA1 protein is expressed in Escherichia coli (E. coli).

Quick Overview for SAA1 Protein (ABIN935202)

Target: SAA1 (Serum Amyloid A1 (SAA1))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 98 % pure

Product Details

Sequence: MRSFFSFLGE AFDGARDMWR AYSDMREANY IGSDKYFHAR GNYDAAKRGP GGVWAAEAIS NARENIQRFF GRGAEDSLAD QAANEWGRSG KDPNHFRPAG LPEKY

Characteristics: Purified recombinant Human ApoSAA1 protein
Expression System: E.coli
Bioactivity: For most in vitro applications, apo-SAA exerts its biological activity in the concentration range of 10-50 µg/mL.

Endotoxin Level: < 0.1 ng per µg (1 EU/µg).

Application Details

Application Notes: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in water to a concentration of 1.0 mg/mL.

Buffer: Lyophilized from 5x PBS.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.

Target Details

Target: SAA1 (Serum Amyloid A1 (SAA1))

Background: Human apo-SAA is a 104 amino acid polypeptide that circulates primarily in association with high-density lipoproteins (HDL). The level of apo-SAA, normally 1-5 ug/ml in plasma, increases 500-1000 fold within 24 hours of an inflammatory stimulus and, under these conditions, is the most abundant HDL apo-lipoprotein. The human SAA gene codes for a 122 amino acid polypeptide, which contains an 18 amino acid N-terminal signal sequence. Recombinant Apo-SAA is a consensus SAA molecule corresponding to human apo-SAA1alpha.
Alternative Names: ApoSAA-1 protein, Human Serum Amyloid A protein, ApoSAA-1 protein, ApoSAA1, ApoSAA-1, ApoSAA 1 protein, ApoSAA 1

Pathways: Toll-Like Receptors Cascades